La Tour du Valat

Institut de recherche pour la conservation des zones humides méditerranéennes

Titre :	The use of a GnRH vaccine to suppress mare ovarian activity in a large group of mares under field conditions
Auteurs :	A. E. Botha, Auteur ; M. L. Schulman, Auteur ; H. J. Bertschinger, Auteur ; A. J. Guthrie, Auteur ; C. H. Annandale, Auteur ; S. B. Hughes, Auteur
Type de document :	Article
Dans :	Wildlife Research (35(6) 2008)
Article en page(s) :	548-554
Langues:	Anglais
Résumé :	The aim of this study was to evaluate the effect of active immunisation against GnRH on ovarian activity and serum progesterone concentrations in a large group of mares (10 control and 55 experimental) under field conditions as a model for wildlife species such as zebra and African elephants. Within the experimental group, mares were subdivided into three age categories: Category 1 (4 years and younger, n = 26), Category 2 (4 - 10 years old, n = 18), and Category 3 (>= 11 years old, n = 11). Experimental mares were vaccinated intramuscularly with 2mL(400 mu g) of the GnRH vaccine Improvac (Pfizer Animal Health, Sandton, South Africa). Control mares received the same amount of saline solution. The vaccinations were repeated 35 days later. The ovaries and reproductive tracts of each mare were examined by means of rectal palpation and ultrasonography on Days 0, 35 and 70. Blood was collected weekly for determination of serum progesterone concentration until Day 175. On Day

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