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Spontaneous Mutation Accumulation Studies in Evolutionary Genetics

Daniel L. Halligan, Auteur ; Peter D. Keightley, Auteur

Dans Annual Review of Ecology, Evolution, and Systematics (40 2009)

Mutation accumulation (MA) experiments, in which mutations are allowed to drift to fixation in inbred lines, have been a principal way of studying the rates and properties of new spontaneous mutations. Phenotypic assays of MA lines inform us abo[...]

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